Acetonitrile (Preparative) 75-05-8
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Acetonitrile (Preparative) 75-05-8
Acetonitrile (Preparative) 75-05-8
Acetonitrile (Preparative) 75-05-8
Preparative-grade Acetonitrile is a high-purity solvent designed for preparative chromatography and pharmaceutical-scale synthesis. It offers consistent solvent strength and low UV absorbance, ensuring reproducible separation results.
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Product Description

English Name Acetonitrile
CAS RN 75-05-8
Molecular Formula C₂H₃N
Molecular Weight 41.05
Structural Formula Acetonitrile (Preparative) 75-05-8
Technical Indicators of Industrial Acetonitrile
Item Quality Indicator
Appearance Colorless transparent liquid, free from suspended particles

 

Item Quality Index (Chromatographic Grade) Quality Index (Preparative Grade)
Appearance Colorless transparent liquid, no suspended matter Colorless transparent liquid, no suspended matter
Color ≤ 10 Hazen ≤ 10 Hazen
Moisture ≤ 200 ppm ≤ 200 ppm
Purity (GC) ≥ 99.9% ≥ 99.9%
Acidity (as H⁺) ≤ 0.05 mmol/100g ≤ 0.05 mmol/100g
Alkalinity (as OH⁻) ≤ 0.02 mmol/100g ≤ 0.02 mmol/100g
Evaporation Residue ≤ 3.0 ppm ≤ 3.0 ppm
Fluorescent Impurities at 254 nm / /
Fluorescent Impurities at 365 nm / /
Fluorescent Impurities at 193 nm / /
Light Transmittance at 195 nm ≥ 75% /
Light Transmittance at 200 nm ≥ 95% ≥ 90%
Light Transmittance at 210 nm / ≥ 94%
Light Transmittance at 220 nm / ≥ 96%

 

Key Features

 

● ≥ 99.9 % purity, UV cutoff ≤ 190 nm

● Low residue after evaporation and minimal water content

● Suitable for scale-up in peptide, nucleotide, and intermediate synthesis

 

Applications

 

● Used in preparative HPLC and flash chromatography

● Solvent for purification of pharmaceutical intermediates

● Ideal for biopharma process development and upscaling

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